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KMID : 0388219950020010019
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Journal of the Korean Rheumatism Association
1995 Volume.2 No. 1 p.19 ~ p.27
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Trace Element Levels in Hair as an Indicator for Disease Activity of Rheumatoid Arthritis
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전재범
김대환/김승영/김평남/정성수/이인홍/배상철/유대현/주경빈
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Abstract
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Objective :
@EN Zinc and copper are the second and third most abundant trace elements following iron in the human body. Zinc and copper have important effects on humoral and cell-mediated immunity. In patients with rheumatoid arthritis, it has been reported
that
serum zinc level is decreased and seurm copper level increased. But no reports are available for the trace element level of hair in patients with rheumatoid arthritis. We studied to investigate the significance of trace element level of hair in
rheumatoid arthritis patients, particularly its relation to disease activity.
@ES Methods :
@EN The t5race element level of hair was estimated in 50 patients with rheumatoid arthritis and 22 osteoarthritis patients by inductively coupled plasma atomic emission spectrometry and was investigate the correlation to various disease activity
indices
of rheumatoid arthritis.
@ES Results :
@EN The results were as follows : 1) There was no significant difference in either the zinc or copper level in hair between patients with rheumatoid arthritis and osteoarthritis. 2) No correlation was observed between the zinc or copper level in
hair
and age or disease duration for rheumatoid arthritis patients. 3) Zinc and copper levels of hair did not correlate with various indices of disease activity in rheumatoid patients.
@ES Conclusions :
@EN Zinc and copper levels of hair in rheumatoid arthritis patients were not different form those of osteoarthritis and did not correlate with disease activity indices. Studies on the effect of antirheumatic drug therapy on trace element level of
hair
are necessary.
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KEYWORD
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